Description
Recombinant Human PTH (1-34) contains the biologically active N-terminal 34 amino acids of human parathyroid hormone. This region is responsible for much of PTH receptor activation and can stimulate intracellular cAMP signaling through PTH1R. PTH signaling plays an important role in calcium regulation, bone metabolism, and the activity of bone-forming and bone-resorbing cells.
The defined 1-34 fragment is widely used in research examining PTH receptor signaling, osteoblast activity, bone formation and resorption, calcium homeostasis, and cellular responses to PTH stimulation. Produced in E. coli and purified to greater than 97%, this recombinant peptide is tested for biological activity in cell-based assays.
GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!
Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.
Recombinant Human Parathyroid Hormone (PHT)
Parathyrin
Parathormone
Parathyroid Hormone 1 (PTH1)
Source: Escherichia coli
MW: ~4.1 kDa (34 amino acids)
Purity: >97% by SDS-PAGE and HPLC analyses
Biological Activity: Fully biologically active when compared to standard. The ED 50 as determined by its ability to induce cAMP accumulation in murine MC3T3E1 cells is less than 50 ng/ml, corresponding to a specific activity of >2.0×104 IU/mg.
Storage/Handling: Store desiccated at -20°C.
HGNC: 9606
NOT FOR HUMAN USE!
Additional resources for this protein may be found at:
OMIM
