Description
Recombinant Human PTH (7-34) is a truncated parathyroid hormone fragment lacking the first six amino acids of the active N-terminus. Unlike PTH (1-34), PTH (7-34) can bind PTH1R without producing the same level of receptor activation, making it useful as a PTH1R antagonist in experimental systems.
This 28 amino acid fragment provides you with a tool for investigating PTH receptor binding, antagonism, cAMP signaling, and the biological consequences of inhibiting PTH1R activation. It can also support studies comparing active and inhibitory PTH fragments in bone, epithelial, and other PTH-responsive cell models.
GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!
Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.
Recombinant Human Parathyroid Hormone (PHT)
Parathyrin
Parathormone
Parathyroid Hormone 1 (PTH1)
Source: Escherichia coli
MW: ~3.4 kDa (28 amino acids)
Purity: >97% by SDS-PAGE and HPLC analyses
Biological Activity: Fully biologically active when compared to standard. The specific activity is determined by UMR106 cell/cAMP method, corresponding to a specific activity of >1.0×104 IU/mg.
Storage/Handling: Store desiccated at -20°C.
HGNC: 9606
NOT FOR HUMAN USE!
Additional resources for this protein may be found at:
OMIM
