Description
The TFEB promoter-luciferase reporter plasmid is designed to study the transcriptional regulation of the TFEB (Transcription Factor EB) gene, a master regulator of autophagy and lysosomal biogenesis. By linking the TFEB promoter to a luciferase reporter gene, researchers can assess how different factors influence the transcriptional activity of the TFEB promoter, and thus, how TFEB expression is regulated under various conditions.
PGC-1α rescues Huntington's disease proteotoxicity by preventing oxidative stress and promoting TFEB function.
The pTFEB promoter-luciferase reporter plasmid is a synthetic plasmid obtained from a third party and its sequence has been confirmed at GoldBio.
Product Specifications
Concentration: 0.2 μg/μL in TE
Volume: 50 μL
Backbone size: 7001 bp
Vector type: Cloning vector
Promoter: TFEB
Bacterial Resistance(s): Ampicillin
Copy number: High Copy
Vector Map
Sequence
GoldBio Vector Map and Sequence for TFEB-promoter-Luciferase-reporter Plasmid
Storage/Handling
TFEB-promoter-Luciferase-reporter Plasmid DNA is at 0.02 μg/μL concentration in TE buffer.
Store all plasmids at -20°C.
