Description
Thiamphenicol is a bacteriostatic antibiotic derived from chloramphenicol. It is effective against several gram-positive and gram-negative bacteria and commonly used in researching protein synthesis and to select for chloramphenicol-resistant transformed cells or the bacterial CAT gene. It can be used against uncomplicated gonorrhea infections and chancroid.
Thiamphenicol functions by binding the 50s ribosomal subunit and inhibiting synthesis of proteins by blocking aminoacyl-tRNA from attaching to the A site. It works by the same mechanism as chloramphenicol, but is about three times as potent.
Product Specifications
Thiamphenicol
MOLECULAR BIOLOGY GRADE
Formula: C12H15Cl2NO5S
MW: 356.22 g/mol
Storage/Handling: Store at 4°C.
This product is light sensitive, and is soluble in acetonitrile, alcohol, dimethylacetamide and dimethylformamide.
PubChem Chemical ID: 27200
