Description
Trimethoprim is a bactericidal antibiotic effective against bacteria responsible for urinary tract infections, prostatitis, and cystitis. It is commonly combined with sulfamethoxazole to combat Staphylococcus aureus.
Trimethoprim functions as a prokaryotic dihydrofolate reductase inhibitor, preventing bacteria from taking up folic acid, which is required to synthesized the nucleotide thymine. Consequently, it is an inhibitor of DNA synthesis.
Product Specifications
Trimethoprim
MOLECULAR BIOLOGY GRADE
Formula: C14H18N4O3
MW: 290.32 g/mol
Storage/Handling: Store at 2-8 °C.
Soluble in chloroform.
PubChem Chemical ID: 5578