Description
Colistin is a cyclic polypeptide antibiotic of the polymyxin family. It targets the cell membrane of bacteria, which ultimately leads to an altered cell permeability and cell death. It primarily targets gram-negative bacteria. Colistin has been used to study mannose-resistant haemagglutination, antibiotic resistance, and nephrotoxicity.
Colistin sulfate (colistin) is the end product of Colistin Sodium Methanesulfonate (CMS) and does not require molecular conversion for antimicrobial properties.
Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.
Product Specifications
Colistin Sulfate, USP Grade
Polymyxin E
Formula: C52H98N16O13 ∙ 2.5 H2SO4
MW: 2,801.26 g/mol
Storage/Handling: Store at 2-8°C.
PubChem Chem ID: 46224602
Air shipments may require special packaging and a small additional box charge.
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