5-Chloroindole-2-carboxylic acid is a reagent for chemical synthesis. It can also be used to reduce cholesterol concentration in blood.

5-Cyanoindole has a variety of applications. It is used to create electropolymer films and can function as an enzyme inhibitor. Additionally, 5-cyanoindole is involved in the preparation of dihydroisoquinolines, benzoylindoles, 4,5-dihydrocyclopenta[c]quinolones, and vinyl indoles.

5-Ethylindole is a reagent used for chemical synthesis. It forms a reactant for the creation of IL2 T-cell (ITK) inhibitors and Sodium-dependent glucose co-transporter 2 inhibitors (SGLT2), along with small molecule C5a receptor modulators and the synthesis of antitumor agents.

5-Ethylindole-2-carboxylic acid is a reagent used for chemical synthesis useful for synthesizing auxin analogs and pharmaceuticals.

5-Ethylindole-3-acetic acid is an auxin analog of indole-3-acetic acid and a reagent for chemical synthesis.

5-Fluoroindole is a reagent involved in a variety of biochemical preparation procedures including: preparation of 5-HT6 receptor ligands, immunosuppressive agents, tryptophan dioxygenase inhibitors, anticancer agents, antibacterial agents, sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors, selective serotonin reuptake inhibitors, and myeloperoxidase inhibitors.

6-azaindole is a reagent used in biochemical synthesis. It can be used as a building block in creating a complex 6-azaindole containing an HIV-1 inhibitor with the prodrug BMS-663068.

6-Benzyloxyindole-3-carboxaldehyde is a cyclic reagent for the creation of organic molecules like substituted naphthylene leukotriene B4 antagonists which are useful as anti-inflammatory agents.

6-Chloroindole is a reagent used for chemical synthesis. When introduced to Claviceps purpurea it produces a substituted L-tryptophan. When reacted with a carboxy group, it can form 5-Carboxy-6-chloroindole, which is a precursor for a p38 kinase inhibitor.

6-Cyanoindole is a reagent for chemical synthesis.