Thrombopoietin (THPO), the ligand for the receptor encoded by the c-Mpl proto-oncogene, is a key regulator of megakaryocytopoiesis and thrombopoiesis in vitro and in vivo. The cDNAs for THPO have recently been cloned from canine, murine and human sources. The proteins from these three species are highly conserved, exhibiting from 69-75% sequence identity at the amino acid level. Two distinct domains, separated by a pair of arginine residues that may be a proteolytic cleavage site, have been identified in THPO: the amino terminal region exhibiting sequence homology to erythropoietin and the carboxy terminal region containing multiple potential N-linked glycosylation sites. Recombinant THPO has been shown to stimulate the maturation, as well as the proliferation, of megakaryocytes and may have important therapeutic applications for the treatment of various clinical conditions associated with thrombocytopenia.

Tiamulin fumarate is a pleuromutilin antibiotic targeting gram-positive bacteria and several Mycoplasma species. It is soluble in aqueous solution.

Pleuromutilin antibiotics target the 50s ribosomal subunit, inhibiting protein synthesis in bacteria, by binding peptidyl transferase. This blocks formation of peptide bonds.

Ticarcillin is a carboxypenicillin used to treat gram-negative bacteria like Pseudomonas aeruginosa and Stenotrophomonas maltophilia. An alternative to ampicillin it can be used to test the presence of marker genes in bacteria, while preventing the appearance of satellite colonies occurring during the ampicillin breakdown. In plants it kills Agrobacterium used to deliver plant cells. A 15:1 mixture of ticarcillin and clavulanate is commonly called TimentinTM is stronger than ticarcillin alone.

Tilmicosin is a macrolide antibiotic structurally similar to tylosin. It targets gram-negative bacteria, especially those responsible for bovine respiratory infections.

Timentin™ is a 15:1 mixture of ticarcillin and clavulanate. Ticarcillin is a penicillin ß-lactam antibiotic, which is susceptible to ß-lactamase degradation. When combined with clavulanate, a ß-lactamase inhibitor, its efficacy is greatly increased. Timentin™ exhibits high activity against gram-negative bacteria and resistant Agrobacterium species.

Timentin™ is a 15:1 mixture of ticarcillin and clavulanate. Ticarcillin is a penicillin ß-lactam antibiotic, which is susceptible to ß-lactamase degradation. When combined with clavulanate, a ß-lactamase inhibitor, its efficacy is greatly increased. Timentin™ exhibits high activity against gram-negative bacteria and resistant Agrobacterium species.

The Timentin™ EZ Pak™ is the fastest and easiest way to make a set amount of sterile Timentin™ solution. The kit includes pre weighed Timentin™ powder, a sterile filter, and a sterile container for the filtered solution. No need to calculate, simply add the stated amount of deionized H2O, filter, and pour into the labeled bottle for easy usage. The EZ Pak™ includes high quality GoldBio Timentin™ and the sterile solution is ready for tissue culture, bacterial media, or any number of uses.

Tissue Cell Lysis Buffer has been developed for extraction of total soluble protein from fresh or frozen animal tissues. Tissue Cell Lysis Buffer is based on an organic buffer, which utilizes a mild non-ionic detergent and a proprietary combination of various salts and agents to enhance extraction and stability of proteins. Depending on the application, additional agents such as chelating agents, reducing agents and protease inhibitors may be added into Tissue Cell Lysis Buffer. Tissue Cell Lysis Buffer reagent has been tested for use with a wide variety of animal tissues.

TMB is an excellent colorimetric substrate for detection of horseradish peroxidase labeled probes and is used with peroxidase and peroxidase-coupled systems, particularly in ELISA techniques. It produces a soluble end product, which is blue in color and can be read spectrophotometrically. TMB has also been used in the quantitative determination of hemoglobin and in cytochemical staining for peroxidase. TMB is a hepatitis B antigen.