Lincosamides
Lincosamides are a class of antibiotic that inhibit bacterial protein synthesis by binding the 23s portion of the 50S ribosomal subunit and interfering with tRNA activity during translation. However, lincosamides do not interfere with protein synthesis in eukaryotic cells because eukaryotic ribosomes are structurally different from bacteria ribosomes. Lincosamides such as clindamycin are broad-spectrum antibiotics that primarily target gram-positive and gram-negative bacteria such as Clostridia and Bacteroides species.
Showing 1-2 of 2 items.
Clindamycin Hydrochloride
| Catalog ID | Size | Pricing | |
|---|---|---|---|
| C-175-10 | 10 g | $ 55.00 | |
| C-175-25 | 25 g | $ 89.00 | |
| C-175-50 | 50 g | $ 145.00 | |
| C-175-100 | 100 g | $ 245.00 |
Description
Clindamycin is a lincosamide antibiotic primarily targeting gram-positive bacteria. It is also against anaerobic bacteria and protozoans such as Toxoplasma species. Clindamycin binds the 50s ribosomal subunit preventing ribosomal translocation, resulting in inhibition of protein synthesis. It has been shown to exhibit synergistic properties when combined with vancomycin.
Product Specifications
| Catalog ID | C-175 |
|---|---|
| CAS # | 21462-39-5 |
| MW | 461.44 g/mol |
| Grade | MOLECULAR BIOLOGY GRADE |
| Storage/Handling | Store desiccated at -20°C. |
Lincomycin HCl, USP Grade
| Catalog ID | Size | Pricing | |
|---|---|---|---|
| L-300-1 | 1 g | $ 76.00 | |
| L-300-5 | 5 g | $ 341.00 |
Description
Lincomycin HCl is a lincosamide antibiotic targeting gram positive and anaerobic bacteria as well as protozoans. It is commonly used to combat Staphylococcus and Streptococcus bacteria. Lincomycin HCl is freely soluble in aqueous solution.
Product Specifications
| Catalog ID | L-300 |
|---|---|
| CAS # | 7179-49-9 |
| MW | 461.01 g/mol |
| Storage/Handling | Store at 4°C. |
