The pSuperAgro® v1 Plasmid (pBBRacdS) is an Agrobacterium helper plasmid that includes 1-aminocyclopropane-1-carboxylate (ACC) deaminase (AcdS) activity, driven by the lac promoter, which suppresses ethylene evolution during co-cultivation and significantly increases T-DNA transfer.

AcdS activity is beneficial for higher callus induction frequency and also suppresses callus browning phenomena. This plasmid has been shown to be efficacious in both Hardy Pampas Grass (E. Ravennae) and Tomato plants (S. Lycopersicum).

These products are sold under license by GoldBio and require a signed agreement before fulfillment. See license details below in the technical documents.

pSuperAgro® v1 was designed to include AcdS activity, driven by the lac promoter, which suppresses ethylene evolution during co-cultivation and significantly increases T-DNA transfer.

AcdS activity is beneficial for higher callus induction frequency and also suppresses callus browning phenomena. This plasmid has been shown to be efficacious in both Hardy Pampas Grass ( E. Ravennae) and Tomato plants (S. Lycopersicum).

pSuperAgro™ v1tet has been modified to provide tetracycline resistance instead of the original pSuperAgro™ V1’s gentamicin resistance. This allows the helper plasmid to be used in conjunction with our other GoldBio Agrobacterium strains, including the widely used GV3101 strain.

These products are sold under license by GoldBio and require a signed agreement before fulfillment. See license details below in the technical documents.

The pSuperAgro® v3 plasmid (pBBRgabT) was designed to include GabT activity, driven by the lac promoter, which degrades gamma-aminobutyric acid (GABA) during co-cultivation. The reduction of GABA significantly increases T-DNA transfer and increases transient and stable transformation frequencies in both tomato and grass plants.

GabT activity decreases GABA content locally in plant cells and induces higher shoot regeneration, decreasing the number of cotyledons used for transformation and reducing the time and labor required for transformation. This plasmid has been shown to be efficacious in both Hardy Pampas Grass ( E. Ravennae) and Tomato plants (S. Lycopersicum).

These products are sold under license by GoldBio and require a signed agreement before fulfillment. See license details below in the technical documentation.

pSuperAgro® v3 was designed to include GabT activity, driven by the lac promoter, which degrades gamma-aminobutyric acid (GABA) during co-cultivation. The reduction of GABA significantly increases T-DNA transfer and increases transient and stable transformation frequencies in both tomato and grass plants.

GabT activity decreases GABA content locally in plant cells and induces higher shoot regeneration, decreasing the number of cotyledons used for transformation and reducing the time and labor required for transformation. This plasmid has been shown to be efficacious in both Hardy Pampas Grass ( E. Ravennae) and Tomato plants (S. Lycopersicum).

pSuperAgro™ v3tet has been modified to provide tetracycline resistance instead of the original pSuperAgro™ V3’s gentamicin with our other GoldBio Agrobacterium strains, including the widely used GV3101 strain.

These products are sold under license by GoldBio and require a signed agreement before fulfillment. See license details below in the technical documents.

pSuperAgro® v4 was designed to include AcdS and GabT activity, driven by a single lac promotor, which both suppresses ethylene evolution and degrades gamma-aminobutyric acid (GABA) during co-cultivation. The combined suppression of ethylene and reduction of GABA significantly increases T-DNA transfer and increases transient and stable transformation frequencies in both tomato and grass plants.

AcdS activity is beneficial for higher callus induction frequency and suppresses callus browning phenomena. GabT activity decreases GABA content locally in plant cells and induces higher shoot regeneration, decreasing the number of cotyledons used for transformation and reducing the time and labor required for transformation. This plasmid has been shown to be efficacious in both Hardy Pampas Grass ( E. Ravennae) and Tomato plants (S. Lycopersicum).

These products are sold under license by GoldBio and require a signed agreement before fulfilment. See license details below in the technical documents.

pSuperAgro® v4 was designed to include AcdS and GabT activity, driven by a single lac promoter, which both suppresses ethylene evolution and degrades gamma-aminobutyric acid (GABA) during co-cultivation. The combined suppression of ethylene and reduction of GABA significantly increases T-DNA transfer and increases transient and stable transformation frequencies in both tomato and grass plants.

AcdS activity is beneficial for higher callus induction frequency and also suppresses callus browning phenomena. GabT activity decreases GABA content locally in plant cells and induces higher shoot regeneration, decreasing the number of cotyledons used for transformation and reducing the time and labor required for transformation. This plasmid has been shown to be efficacious in both Hardy Pampas Grass ( E. Ravennae) and Tomato plants (S. Lycopersicum).

pSuperAgro™ v4tet has been modified to provide tetracycline resistance instead of the original pSuperAgro™ V4’s gentamicin resistance. This allows the helper plasmid to be used in conjunction with our other GoldBio strains, including the widely used GV3101 strain.

These products are sold under license by GoldBio and require a signed agreement before fulfillment. See license details below in the technical documents.

Human Parathyroid Hormone (PTH) is a hormone expressed and secreted as preproPTH by chief cells of the parathyroid glands when extracellular calcium levels are low. It is coexpressed with furin, the enzyme believed to be responsible for processing proPTH to PTH. PTH is a ligand for two different receptors, PTH1R in bone and kidney and PTH2R found in the CNS, pancreas, and placenta. PTH plays a major role in bone metabolism and calcium homeostasis, as well as renal excretion. Recombinant PTH (1-34) has been used to stimulate bone formation and bone resorption, increasing or decreasing bone mass depending on the mode of administration.

Human Parathyroid Hormone (PTH) is a hormone expressed and secreted as preproPTH by chief cells of the parathyroid glands when extracellular calcium levels are low. It is coexpressed with furin, the enzyme believed to be responsible for processing proPTH to PTH. PTH is a ligand for two different receptors, PTH1R in bone and kidney and PTH2R found in the CNS, pancreas, and placenta. PTH plays a major role in bone metabolism and calcium homeostasis, as well as renal excretion. In osteoblasts, PTH stimulates glycogenesis and the uptake of [1-(14)C]-2-deoxy-D-glucose (2DG).

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Human Parathyroid Hormone (PTH) is a hormone expressed and secreted as preproPTH by chief cells of the parathyroid glands when extracellular calcium levels are low. It is coexpressed with furin, the enzyme believed to be responsible for processing proPTH to PTH. PTH is secreted as a midregional peptide fragment (7-34) when extracellular calcium levels are high, offsetting the effects of PTH. PTH plays a major role in bone metabolism and calcium homeostasis, as well as renal excretion. PTH (7-34) is a PTH1R antagonist capable of stimulating proliferation and differentiation of hair follicles and epidermis while promoting cell survival by activation of Akt.

GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

Human Parathyroid Hormone (PTH) is a hormone expressed and secreted as preproPTH by chief cells of the parathyroid glands when extracellular calcium levels are low. PTH is coexpressed with furin, the enzyme believed to be responsible for processing proPTH to PTH. PTH is secreted as a C-terminal fragment (7-84) when extracellular calcium levels are high, offsetting the effects of PTH. PTH (7-84) acts as an antagonist for PTH1R, as well as a possible carboxy-terminus interacting PTH receptor. PTH and truncated PTH fragments play a major role in bone metabolism and calcium homeostasis, as well as renal excretion. This particular product has been labeled with the stable 15N isotope to help track its activity.

Human Parathyroid Hormone (PTH) is a hormone expressed and secreted as preproPTH by chief cells of the parathyroid glands when extracellular calcium levels are low. PTH is coexpressed with furin, the enzyme believed to be responsible for processing proPTH to PTH. PTH is secreted as a C-terminal fragment (7-84) when extracellular calcium levels are high, offsetting the effects of PTH. PTH (7-84) acts as an antagonist for PTH1R, as well as a possible carboxy-terminus interacting PTH receptor. PTH and truncated PTH fragments play a major role in bone metabolism and calcium homeostasis, as well as renal excretion.

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Parathyroid hormone (PTH) is a single polypeptide of 84 amino acids. It is a critical hormone in the regulation of Ca2+ homeostasis and is secreted by the parathyroid glands. These glands promote the release of calcium from bone into the blood stream by activating osteoblasts and inhibiting osteoclasts. Secretion of PTH increases when the level of calcium in the extracellular fluid is low. When there is more Ca2+ in the blood, there is increased intestinal absorption of calcium, renal tubular reabsorption of calcium and increased renal excretion of phosphates. Therefore, PTH is a major regulator of bone metabolism.