BMP7, Human Inactive Protein
Recombinant Human Bone Morphogenetic Protein 7, Inactive Protein
osteogenic protein 1
Bone Morphogenetic Proteins (BMPs) belong to the TGF-β (Transforming Growth Factor) superfamily of structurally related signaling proteins. BMP7 is one of at least 15 structurally and functionally related BMPs, originally identified as protein regulators of cartilage and bone formation which have since been shown to be involved in embryogenesis and morphogenesis of various tissues and organs. BMPs have been shown to regulate the growth, differentiation, chemotaxis and apoptosis of a variety of cell types; including mesenchymal cells, epithelial cells, hematopoietic cells and neuronal cells. The active form of BMP7 can consist of a dimer of two identical proteins or a heterodimer of two related BMPs. BMP7 is expressed highest in the kidneys and is genetically linked in mice to eye, skeletal and kidney development.
BMP7 Inactive protein is an excellent molecular marker for Western blotting and ELISA or as the molecular standard in detecting secreted BMP7 in reduced SDS-Page gels. It can also be used for preparing antibodies for the BMP7 monomer.
Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.
Source: Escherichia coli
MW: ~15.6 kDa (139 amino acid)
Purity: >95% by SDS-PAGE and HPLC analyses
Biological Activity: Not biologically active.
Storage/Handling: Store desiccated at -20°C.
HGNC ID: 1074
NOT FOR HUMAN USE!
Additional resources for this protein may be found at:
|Storage/Handling||Store desiccated at -20°C.|