α-D-Fucose

Product Description

α-D-Fucose is a six-carbon deoxy monosaccharide. It is equivalent to 6-deoxy-D-galactose. D-fucose acts as a non-metabolizable analogue of L-arabinose and inhibits induction of the L-arabinose operon in some bacteria. Some resistant bacteria possess a mutant araC gene where D-fucose acts as a gratuitous inducer of the L-arabinose operon. D-fucose induces β-galactosidase to some extent in Lactobacillus plantarum.

α-D-fucose inhibits the eukaryotic enzyme Lysine-specific demethylase 1 (LSD1A), thereby causing gene repression. α-D-fucose is being explored in treatments for neurodegenerative diseases because of its effect on gene repression. Seen upregulated in many cancers, LSD1A overexpression pushes the cell cycle of otherwise non-transformed cells so α-D-fucose is being explored in cancers treatments as well.

Product Specifications
6-Deoxy-D-galactopyranose;
α-D-Fuc;
Rhodeose;

Formula: C6H12O5

MW: 164.16 g/mol

PubChem Chemical ID: 444200

Storage/Handling: Store at 4°C

Product Specifications

Catalog ID F-850
CAS # 3615-37-0
MW 164.16 g/mol
Storage/Handling Store at 4°C.

Technical Documentation

P Protocol
O Other
C Certificate of Analysis
S Safety Data Sheet

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