Cefditoren sodium

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Description

Cefditoren sodium is sodium salt of a β-lactam cephalosporin antibiotic that disrupts peptidoglycan synthesis of bacterial cell walls. Cefditoren sodium has been used in comparative studies to ascertain effectiveness of newly synthesized antibiotics as well as in vitro testing of antibiotic resistance in bacteria.

Cephalosporins are a type of β-lactam antibiotic consisting of a four-membered β-lactam ring bound to a six-membered dihydrothiazine ring. This two-ring system causes distortion of the β-lactam amide bond, resulting in decreased resonance stabilization and increased reactivity. β-lactams inhibit the formation of peptidoglycan cross-links within bacterial cell walls by targeting penicillin-binding proteins or PBPs. Consequently, the bacterial cell wall becomes weak and cytolysis occurs. Cephalosporins are less susceptible to β-lactamases than the penicillin β-lactam antibiotics.


Product Specifications
Cefditoren sodium

Formula: C19H17N6NaO5S3

MW: 528.56 g/mol

Storage/Handling: Store at -20°C.

PubChem Chemical ID: 23673042

Cefditoren sodium

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Catalog Number:
C-925-1
CAS Number:
104146-53-4
$138.00

For research use only. Not for food, drug, household, or cosmetic use.
Availability:
2-3 Weeks
Shipping:
$14.99 Ground shipping (In continental US only.)

    Description

    Cefditoren sodium is sodium salt of a β-lactam cephalosporin antibiotic that disrupts peptidoglycan synthesis of bacterial cell walls. Cefditoren sodium has been used in comparative studies to ascertain effectiveness of newly synthesized antibiotics as well as in vitro testing of antibiotic resistance in bacteria.

    Cephalosporins are a type of β-lactam antibiotic consisting of a four-membered β-lactam ring bound to a six-membered dihydrothiazine ring. This two-ring system causes distortion of the β-lactam amide bond, resulting in decreased resonance stabilization and increased reactivity. β-lactams inhibit the formation of peptidoglycan cross-links within bacterial cell walls by targeting penicillin-binding proteins or PBPs. Consequently, the bacterial cell wall becomes weak and cytolysis occurs. Cephalosporins are less susceptible to β-lactamases than the penicillin β-lactam antibiotics.


    Product Specifications
    Cefditoren sodium

    Formula: C19H17N6NaO5S3

    MW: 528.56 g/mol

    Storage/Handling: Store at -20°C.

    PubChem Chemical ID: 23673042

    Product Specifications

    Catalog ID: C-925
    CAS #: 104146-53-4
    MW: 528.56 g/mol
    Storage/handling: Store at -20°C.
    PubChem Chemical ID: 23673042
    IUPAC Name: sodium (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[(Z)-2-(4-methyl-1,3-thiazol-5-yl)ethenyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
    InChI: InChI=1S/C19H18N6O5S3.Na/c1-8-11(33-7-21-8)4-3-9-5-31-17-13(16(27)25(17)14(9)18(28)29)23-15(26)12(24-30-2)10-6-32-19(20)22-10;/h3-4,6-7,13,17H,5H2,1-2H3,(H2,20,22)(H,23,26)(H,28,29);/q;+1/p-1/b4-3-,24-12-;/t13-,17-;/m1./s1
    InChIKey: VFUMWBZIKOREOO-WSWQWPGSSA-M
    SMILES: CC1=C(SC=N1)C=CC2=C(N3C(C(C3=O)NC(=O)C(=NOC)C4=CSC(=N4)N)SC2)C(=O)[O-].[Na+]

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