Description
Sulfadoxine is a broad-spectrum sulfonamide antibiotic effective against gram-negative and gram-positive bacteria. It is commonly used against malaria, especially Plasmodium falciparum malaria with chloroquine resistance. It has been used to study Toxoplasma gondii infections and to prevent infections in post-surgical animal models.
Sulfonamide antibiotics are derived from a chemical called sulfanilamide. They function through inhibiting the conversion of p-aminobenzoic acid to dihydropteroate, an essential step in the synthesis of folic acid. By preventing the production of folate in bacteria, the sulfonamide antibiotics ultimately suppress bacterial DNA replication.
Product Specifications
Sulfadoxine
Sulphadoxine
MOLECULAR BIOLOGY GRADE
Formula: C12H14N4O4S
MW: 310.33 g/mol
Storage/Handling: Store at -20°C.
PubChem Chemical ID: 17134
