Sulfadoxine (Sulphadoxine)

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Description

Sulfadoxine is a broad-spectrum sulfonamide antibiotic effective against gram-negative and gram-positive bacteria. It is commonly used against malaria, especially Plasmodium falciparum malaria with chloroquine resistance. It has been used to study Toxoplasma gondii infections and to prevent infections in post-surgical animal models.

Sulfonamide antibiotics are derived from a chemical called sulfanilamide. They function through inhibiting the conversion of p-aminobenzoic acid to dihydropteroate, an essential step in the synthesis of folic acid. By preventing the production of folate in bacteria, the sulfonamide antibiotics ultimately suppress bacterial DNA replication.


Product Specifications
Sulfadoxine
Sulphadoxine

MOLECULAR BIOLOGY GRADE

Formula: C12H14N4O4S

MW: 310.33 g/mol

Storage/Handling: Store at -20°C.

PubChem Chemical ID: 17134

Sulfadoxine (Sulphadoxine)

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Catalog Number:
S-550-10
CAS Number:
2447-57-6
$85.00

For research use only. Not for food, drug, household, or cosmetic use.
Availability:
2-3 Weeks
Shipping:
$14.99 Ground shipping (In continental US only.)

    Description

    Sulfadoxine is a broad-spectrum sulfonamide antibiotic effective against gram-negative and gram-positive bacteria. It is commonly used against malaria, especially Plasmodium falciparum malaria with chloroquine resistance. It has been used to study Toxoplasma gondii infections and to prevent infections in post-surgical animal models.

    Sulfonamide antibiotics are derived from a chemical called sulfanilamide. They function through inhibiting the conversion of p-aminobenzoic acid to dihydropteroate, an essential step in the synthesis of folic acid. By preventing the production of folate in bacteria, the sulfonamide antibiotics ultimately suppress bacterial DNA replication.


    Product Specifications
    Sulfadoxine
    Sulphadoxine

    MOLECULAR BIOLOGY GRADE

    Formula: C12H14N4O4S

    MW: 310.33 g/mol

    Storage/Handling: Store at -20°C.

    PubChem Chemical ID: 17134

    Product Specifications

    Catalog ID: S-550
    CAS #: 2447-57-6
    Formula: C12H14N4O4S
    MW: 310.33 g/mol
    Grade: MOLECULAR BIOLOGY GRADE
    Storage/handling: Store at -20°C.
    PubChem Chemical ID: 17134
    IUPAC Name: 4-amino-N-(5,6-dimethoxypyrimidin-4-yl)benzenesulfonamide
    InChI: InChI=1S/C12H14N4O4S/c1-19-10-11(14-7-15-12(10)20-2)16-21(17,18)9-5-3-8(13)4-6-9/h3-7H,13H2,1-2H3,(H,14,15,16)
    InChIKey: PJSFRIWCGOHTNF-UHFFFAOYSA-N
    SMILES: COC1=C(N=CN=C1OC)NS(=O)(=O)C2=CC=C(C=C2)N

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