IL36RN (IL-36RA), Murine

Product Description

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Recombinant Murine Inerleukin-36RN
Interleukin 1 Receptor Antagonist Homolog 1 (IL1HY1)
Interleukin 1 Family, Member 5 (IL1F5)
Family of Interleukin 1-δ (FIL1-δ)

Interleukin-36 receptor antagonist (IL36RN) is a secreted protein that belongs to the interleukin 1 cytokine family (IL1 family) and is predominantly expressed in keratinocytes, but not in fibroblasts, endothelial cells or melanocytes. IL36RN has been reported to antagonize the biological activity of IL36A (IL1F6), IL36B (IL1F8), and IL36G (IL1F9). Furthermore, it could constitute part of an independent signaling system analogous to IL1A, IL1B receptor agonist and interleukin-1 receptor type I (IL1R1). In addition, the receptor for IL36RN has not been positively identified; however there is indirect evidence that suggests IL1Rrp2 is the receptor. Recombinant murine IL36 RN contains 154 amino acid residues and shares 91% amino acid sequence identity with human IL36RN.

Sterile Filtered White Lyophilized Powder. Purified and tested for use in cell culture.

Source: Escherichia coli

MW: ~16.9 kDa (154 amino acids)

Purity: >95% by SDS-PAGE and HPLC analyses.

Storage/Handling: Store desiccated at -20°C.


MGI: 1859325

Cross-species homology

Percent Similarity

HuIL36RN *** 90.9
MuIL36RN *** ***

Additional resources for this protein may be found at:

Product Specifications

Catalog ID 1310-36G
MW ~16.9 kDa
Storage/Handling Store desiccated at -20°C.

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