N_Products

Chromogenic substrate, yielding a soluble yellow chromophor for the colorimetric assay of α-L-fucosidase, especially in human serum.

4-Nitrophenyl-β-D-fucopyranoside is a chromogenic substrate for β-D-Fucosidase which yields a yellow solution upon cleavage.

4-Nitrophenyl-β-D-mannopyranoside is a chromogenic β-mannosidase substrate which yields a yellow solution upon cleavage.

4-Nitrophenyl-β-D- xylopyranoside is a chromogenic β-xylosidase substrate, yielding a yellow solution upon cleavage.

Nitrophenyl-β-D-glucopyranoside acts as a chromogenic substrate for β-Glucosidase. When cleaved, Nitrophenyl-β-D-glucopyranoside produces a yellow solution, and its appearance can be measured spectrophotometically.

The study of β-Glucosidase is particularly important as this enzyme is necessary for cell wall degradation and is inherent in some fungi and bacterial pathogens.

5-Nitro-DL-tryptophan is a tryptophan derivative commonly used in biochemical research applications.

5-Nitroindole is a reagent involved in the synthesis of a variety of biochemical compounds, including: 2-oxo-1-pyrrolidine analogs, mGlu4 allosteric modulators, protein kinase inhibitors, antiproliferative agents, anti-HIV 1 agents, antifungal agents, anti-leukemic agents, antivascular agents, anticancer agents, and cannabinoid receptor type 1 (CB1) antagonists.

6-Nitroindole is a reagent used in chemical synthesis. It is a universal base with oligodeoxynucleotides. It has been used in the synthesis of several DNA and RNA based modulators and inhibitors.

6-Nitroindoline is a reagent used in chemical synthesis. It has been used in the synthesis of 5-HT1 receptor agonists, 5-HT2C/2B receptor antagonists, serine protease inhibitors and vanilloid receptor ligands.

7-Nitroindole is a reagent used in chemical synthesis. It has been used in the synthesis of protein kinase and inosine monophosphate inhibitors, beta3 agonists and CCK-1 receptor modulators. 7-Nitroindole has also been used as a photochemical precursor of the 2’-deoxyribonolactone analog.

alpha-Naphthoflavone is a flavone derivative. It functions as an inhibitor of aromatase, which converts testosterone to estrogen, cytochrome P-450 in the liver, and dioxin receptors. alpha-Naphthoflavone induces vasorelaxation through induction of extracellular calcium.

Biotin‐NHS ester reagent enables simple and efficient biotin labeling of amine-containing organic molecules, antibodies, proteins and any other primary amine-containing biomolecules in solution. NH2-activated biotins require an organic solvent such as DMSO or DMF to be dissolved.

Biotin‐PEG4‐NHS Ester is a pegylated, highly hydrophilic biotinylation reagent for simple and efficient biotin labeling of antibodies, proteins and other primary amine-containing biomolecules.

Biotin‐PEG4‐NHS Ester reacts specifically and efficiently with primary amines (e.g., side chain of lysine residues or aminosilane-coated surfaces) at pH 7-9 to form covalent bonds. The hydrophilic polyethylene glycol (PEG) spacer arm of this reagent imparts water solubility that is transferred to the labeled molecule, thus reducing aggregation of labeled proteins stored in solution. The PEG spacer arm also gives the reagent a long and flexible connection to minimize steric hindrance involved with binding to avidin molecules.

Cy3‐NHS Ester is an amine-reactive Cy3 labeling dye that carries only one reactive group on each dye molecule for accurate labeling of amine groups on antibodies or oligonucleotides.

Cy3 is a bright, photostable, and pH insensitive fluorescent dye used to label antibody, proteins, peptides. Cy3 conjugates give less background than TAMRA and most other fluorophores.

Cy3 dyes are water-soluble labeling reagent. Cy3 conjugates can be excited maximally at 550 nm, with peak emission at 570 nm. For fluorescence microscopy, Cy3 can be visualized with traditional TAMRA (tetramethylrhodamine) filter sets since the excitation and emission spectra are nearly identical to those of TAMRA.

Cy5‐NHS Ester is an amine-reactive Cy5 labeling dye that carries only one reactive group on each dye molecule for accurate labeling of amine groups on antibodies or oligonucleotides.

Cy5 dyes are one of most widely used NIR fluorescent dyes. Cy5 conjugates are very bright, photostable, pH insensitive and produce minimal autofluorescence of biological specimens in this region of the spectrum.

Fluorescence of this long-wavelength Cy5 dye is not visible to the human eye but is readily detected by most imaging systems.

Cy5 dyes are water-soluble labeling reagent. Cy5 conjugates are excited maximally at 648 nm and fluoresce maximally at 665 nm. They are excited to about 98% of maximum with a krypton/argon laser (647 nm line) or to about 63% of maximum with a helium/neon laser (633 nm line).