Peptide Hormones

Peptide hormones are products of translation that get secreted from cells and serve as signaling molecules to regulate physiological activities. Secretion of these hormones is tightly regulated by series of feedback loops. Target tissues of these hormones generally possess membrane receptors with high affinity so as to interact with the low circulating concentrations of the hormones. Binding of a peptide hormone to a receptor results in signal transduction and the activation of intracellular secondary messengers. GoldBio offers a variety of affordable, high quality peptide hormones that each elicit different responses related to growth and metabolism. Other peptide hormones are listed in more specific categories (neurotrophic factors, interleukins, etc.).
Showing 1-20 of 23 items.

CYR61, Human

Catalog ID Size Pricing
1150-18-5 5 μg $ 76.00
1150-18-20 20 μg $ 112.00
1150-18-1000 1000 μg $ 1,795.00

Description

Cysteine-rich angiogenic inducer 61 (Cyr61) is a dynamically expressed, multifunctional matricellular protein of the CCN family encoded by the Cyr61 gene. Cyr61 is critical for cardiovascular development during embryogenesis and regulates inflammation, wound healing and fibrogenesis in the adult. It is involved in cell adhesion, cell migration, cell proliferation, and cell differentiation. Cyr61 consists of four domains: an IGFBP domain, a VWF type C domain, a TSP type I domain, and a cysteine knot domain.

Product Specifications

Catalog ID 1150-18
MW ~39.4 kDa
Storage/Handling Store desiccated at -20°C.
View
Quick Add
1150-18-5 5 μg $ 76.00
1150-18-20 20 μg $ 112.00
1150-18-1000 1000 μg $ 1,795.00

IGF1 DES, Human

Catalog ID Size Pricing
1150-01B-20 20 μg $ 76.00
1150-01B-100 100 μg $ 112.00
1150-01B-1000 1000 μg $ 135.00

Description

IGF1 belongs to the insulin gene family. It is a mitogenic polypeptide growth factor that stimulates the proliferation and survival of various cell types including muscle, bone, and cartilage tissue in vitro. IGF1 DES is a truncated variant of human IGF1 with the tripeptide Gly-Pro-Glu absent from the N-terminus. It has been isolated from bovine colostrum, human brain, and porcine uterus. The IGF1 DES is believed to result from post-translational cleavage of IGF1 via protease activity. It is about 10-fold more potent than IGF1 at stimulating hypertrophy and proliferation of cultured cells, a consequence of much reduced binding to IGF-binding proteins, which is in turn caused by the absence of the glutamate at position 3. Clinical opportunities for IGF1-DES have not yet been evaluated, but could apply in catabolic states as well as for the treatment of inflammatory bowel diseases.

Product Specifications

Catalog ID 1150-01B
MW ~7.4 kDa
Storage/Handling Store desiccated at -20°C.
View
Quick Add
1150-01B-20 20 μg $ 76.00
1150-01B-100 100 μg $ 112.00
1150-01B-1000 1000 μg $ 135.00

IGF1, 15N, Human

Catalog ID Size Pricing
1150-01N-10 10 μg $ 76.00
1150-01N-50 50 μg $ 112.00
1150-01N-250 250 μg $ 280.00
1150-01N-500 500 μg $ 428.00
1150-01N-1000 1000 μg $ 701.00

Description

The Insulin-like growth factors (IGFs) are mitogenic polypeptide growth factors, predominantly produced in the liver, that stimulate the proliferation and survival of various cell types, including muscle, bone and cartilage tissue in vitro. IGFs belong to the Insulin gene family and are similar by structure and function to insulin, but have a much higher growth-promoting activity. IGF1 expression is regulated by growth hormone, while IGF2 expression is influenced by placenta lactogen. Both IGF1 and IGF2 signal through the tyrosine kinase type I receptor (IGFIR). Mature IGFs are generated through proteolytic processing of inactive precursor proteins. Recombinant human IGF1 is a globular protein containing 70 amino acids and 3 intra-molecular disulfide bonds. This particular product has been labeled with the stable 15N isotope to help track its activity.

Product Specifications

Catalog ID 1150-01N
MW ~7.7 kDa
Storage/Handling Store desiccated at -20°C.
View
Quick Add
1150-01N-10 10 μg $ 76.00
1150-01N-50 50 μg $ 112.00
1150-01N-250 250 μg $ 280.00
1150-01N-500 500 μg $ 428.00
1150-01N-1000 1000 μg $ 701.00

IGF1, Human

Catalog ID Size Pricing
1150-01-100 100 μg $ 76.00
1150-01-500 500 μg $ 112.00
1150-01-1000 1000 μg $ 135.00

Description

The Insulin-like growth factors (IGFs) are mitogenic polypeptide growth factors that stimulate the proliferation and survival of various cell types, including muscle, bone and cartilage tissue in vitro. They are predominantly produced in the liver. IGFs belong to the Insulin gene family and are similar by structure and function to insulin, but have a much higher growth-promoting activity. IGF1 expression is regulated by growth hormone, while IGF2 expression is influenced by placenta lactogen. Both IGF1 and IGF2 signal through the tyrosine kinase type I receptor (IGF IR). Mature IGFs are generated through proteolytic processing of inactive precursor proteins. Recombinant human IGF1 is a globular protein containing 70 amino acids, and 3 intra-molecular disulfide bonds.

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Product Specifications

Catalog ID 1150-01
MW ~7.6 kDa
Storage/Handling Store desiccated at -20°C.
View
Quick Add
1150-01-100 100 μg $ 76.00
1150-01-500 500 μg $ 112.00
1150-01-1000 1000 μg $ 135.00

IGF1, LR3, Human (Media Grade)

Catalog ID Size Pricing
1150-03-1 1 mg $ 120.00
1150-03-5 5 mg $ 362.00
1150-03-20 20 mg $ 827.00
1150-03-50 50 mg $ 1,811.00

Description

The Insulin-like growth factors (IGFs) are mitogenic polypeptide growth factors, predominantly produced in the liver, that stimulate the proliferation and survival of various cell types, including muscle, bone and cartilage tissue in vitro. IGFs belong to the Insulin gene family and are similar by structure and function to insulin, but have a much higher growth-promoting activity. IGF1 expression is regulated by growth hormone, while IGF2 expression is influenced by placenta lactogen. Both IGF1 and IGF2 signal through the tyrosine kinase type I receptor (IGF IR). Mature IGFs are generated through proteolytic processing of inactive precursor proteins. Recombinant human IGF1 is a globular protein containing 70 amino acids and 3 intra-molecular disulfide bonds.


The LR3 IGF1 has a substitution of arginine for the glutamic acid at position 3 of human IGF1 and an extension of 13 amino acid residues. This change of sequence causes it to have a much longer half-life and is specifically designed and manufactured for mammalian cell culture to support large-scale manufacturing of recombinant biopharmaceuticals.

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Product Specifications

Catalog ID 1150-03
MW ~9.1 kDa
Storage/Handling Store desiccated at -20°C.
View
Quick Add
1150-03-1 1 mg $ 120.00
1150-03-5 5 mg $ 362.00
1150-03-20 20 mg $ 827.00
1150-03-50 50 mg $ 1,811.00

IGF1, LR3, Human (Receptor Grade)

Catalog ID Size Pricing
1150-03U-100 100 μg $ 66.00
1150-03U-1000 1 mg $ 132.00
1150-03U-10 10 mg $ 656.00

Description

The Insulin-like growth factors (IGFs) are mitogenic polypeptide growth factors, predominantly produced in the liver, that stimulate the proliferation and survival of various cell types, including muscle, bone and cartilage tissue in vitro. IGFs belong to the Insulin gene family and are similar by structure and function to insulin, but have a much higher growth-promoting activity. IGF1 expression is regulated by growth hormone, while IGF2 expression is influenced by placenta lactogen. Both IGF1 and IGF2 signal through the tyrosine kinase type I receptor (IGF IR). Mature IGFs are generated through proteolytic processing of inactive precursor proteins. Recombinant human IGF1 is a globular protein containing 70 amino acids and 3 intra-molecular disulfide bonds.

Product Specifications

Catalog ID 1150-03U
MW ~9.1 kDa
Storage/Handling Store desiccated at -20°C.
View
Quick Add
1150-03U-100 100 μg $ 66.00
1150-03U-1000 1 mg $ 132.00
1150-03U-10 10 mg $ 656.00

IGF1, Murine

Catalog ID Size Pricing
1350-01-10 10 μg $ 76.00
1350-01-50 50 μg $ 112.00
1350-01-100 100 μg $ 143.00
1350-01-250 250 μg $ 274.00
1350-01-500 500 μg $ 416.00
1350-01-1000 1000 μg $ 739.00

Description

The Insulin-like growth factors (IGFs) are mitogenic polypeptide growth factors, predominantly produced in the liver, that stimulate the proliferation and survival of various cell types, including muscle, bone and cartilage tissue in vitro. IGFs belong to the Insulin gene family and are similar by structure and function to insulin, but have a much higher growth-promoting activity. IGF1 expression is regulated by growth hormone, while IGF2 expression is influenced by placenta lactogen. Both IGF1 and IGF2 signal through the tyrosine kinase type I receptor (IGFIR). Mature IGFs are generated through proteolytic processing of inactive precursor proteins. Recombinant murine IGF1 is a globular protein containing 70 amino acids, and 3 intra-molecular disulfide bonds.

Product Specifications

Catalog ID 1350-01
MW ~7.7 kDa
Storage/Handling Store desiccated at -20°C.
View
Quick Add
1350-01-10 10 μg $ 76.00
1350-01-50 50 μg $ 112.00
1350-01-100 100 μg $ 143.00
1350-01-250 250 μg $ 274.00
1350-01-500 500 μg $ 416.00
1350-01-1000 1000 μg $ 739.00

IGF1, Rat

Catalog ID Size Pricing
1550-01-10 10 μg $ 76.00
1550-01-50 50 μg $ 112.00
1550-01-100 100 μg $ 152.00
1550-01-250 250 μg $ 291.00
1550-01-500 500 μg $ 436.00
1550-01-1000 1000 μg $ 781.00

Description

The Insulin-like growth factors (IGFs) are mitogenic polypeptide growth factors that stimulate the proliferation and survival of various cell types including muscle, bone, and cartilage tissue in vitro. They are predominantly produced in the liver. IGFs belong to the Insulin gene family and are similar by structure and function to insulin, but have a much higher growth-promoting activity. IGF1 expression is regulated by growth hormone, while IGF2 expression is influenced by placenta lactogen. Both IGF1 and IGF2 signal through the tyrosine kinase type I receptor (IGF IR). Mature IGFs are generated through proteolytic processing of inactive precursor proteins. Recombinant human IGF1 is a globular protein containing 70 amino acids, and 3 intra-molecular disulfide bonds.

Product Specifications

Catalog ID 1550-01
MW ~7.7 kDa
Storage/Handling Store desiccated at -20°C.
View
Quick Add
1550-01-10 10 μg $ 76.00
1550-01-50 50 μg $ 112.00
1550-01-100 100 μg $ 152.00
1550-01-250 250 μg $ 291.00
1550-01-500 500 μg $ 436.00
1550-01-1000 1000 μg $ 781.00

IGFBP3, Human

Catalog ID Size Pricing
1150-01B3-5 5 μg $ 76.00
1150-01B3-25 25 μg $ 112.00
1150-01B3-100 100 μg $ 324.00
1150-01B3-250 250 μg $ 580.00
1150-01B3-500 500 μg $ 900.00
1150-01B3-1000 1000 μg $ 1,437.00

Description

Insulin-like Growth Factor-Binding Protein 3 (IGFBP3) belongs to the IGFBP family, which are all proteins with conserved cysteine residues, an IGFBP domain, and a thyroglobulin type-I domain. IGFBP3 is expressed by most tissues and is the most abundant IGFBP protein. It has higher levels of expression during postnatal life, which peak during puberty. The expression of IGFBP3 in fibroblasts is stimulated by a number of mitogenic growth factors. The protein forms a ternary complex with IGFI or IGFII, and an acid-labile subunit, causing it to circulate in the plasma. As this complex, it prolongs the half-life of IGFs and alters their interaction with cell surface receptors. Decreased plasma levels of IGFBP3 often happen during the progression of prostate cancer from benign to metastatic disease.

Product Specifications

Catalog ID 1150-01B3
MW ~28.8 kDa
Storage/Handling Store desiccated at -20°C.
View
Quick Add
1150-01B3-5 5 μg $ 76.00
1150-01B3-25 25 μg $ 112.00
1150-01B3-100 100 μg $ 324.00
1150-01B3-250 250 μg $ 580.00
1150-01B3-500 500 μg $ 900.00
1150-01B3-1000 1000 μg $ 1,437.00

IGFBP7, Human

Catalog ID Size Pricing
1150-01B7-5 5 μg $ 76.00
1150-01B7-25 25 μg $ 112.00
1150-01B7-1000 1000 μg $ 1,437.00

Description

IGFBP7 belongs to the superfamily of insulin-like growth factor (IGF) binding proteins and is encoded by the IGFBP7 gene in human. It is expressed in a wide range of normal human tissues and it generally shows reduced expression in cancer cell lines of prostate, breast, colon, and lung origin. IGFBP7 includes conserved cysteine residues. IGFBP7 modulates the biological activities of IGF proteins. It also suppresses growth and colony formation of prostate and breast cancer cell lines. Above all, IGFBP7 is a very important factor in skeletal myogenesis. Human IGFBP7 cDNA encodes a 282 amino acid (a.a.) residue precursor protein with a putative 26 a.a. signal peptide.

Product Specifications

Catalog ID 1150-01B7
MW ~26.4 kDa
Storage/Handling Store desiccated at -20°C.
View
Quick Add
1150-01B7-5 5 μg $ 76.00
1150-01B7-25 25 μg $ 112.00
1150-01B7-1000 1000 μg $ 1,437.00

Leptin, Human

There is no image for Leptin, Human Leptin, Human
Catalog ID Size Pricing
3110-06-200 200 μg $ 76.00
3110-06-1000 1000 μg $ 112.00
3110-06-5000 5000 μg $ 280.00

Description

Human Leptin is a hormone expressed and secreted primarily by adipose tissues, though also produced by a variety of other cells at lower levels. It is a ligand for the leptin receptor (LEPR) that is expressed at highest levels in the hypothalamus. Leptin’s primary role is in the regulation of energy balance in the body, stimulating energy expenditure while inhibiting hunger. It inhibits the activity of neuropeptide Y and downregulates the expression of endocannabinoids, while upregulating expression of α-melanocyte-stimulating hormone. Obesity is correlated with a receptor desensitization to leptin that leaves the eater hungry despite high energy stores. Leptin also plays a role in hematopoiesis, angiogenesis, ossification, inflammation, and immune responses.

Product Specifications

Catalog ID 3110-06
MW ~16.0 kDa
Storage/Handling Store desiccated at -20°C.
View
Quick Add
3110-06-200 200 μg $ 76.00
3110-06-1000 1000 μg $ 112.00
3110-06-5000 5000 μg $ 280.00

NOV, Human

Catalog ID Size Pricing
1150-01B9-5 5 μg $ 76.00
1150-01B9-20 20 μg $ 112.00
1150-01B9-1000 1000 μg $ 1,795.00

Description

NOV is a dynamically expressed, multifunctional matricellular protein of the CCN (CTGF/CYR61/NOV) family encoded by the NOV gene. It is expressed in certain tumors, including Wilm’s tumor and most nephroblastomas. Expression of NOV has been reported to reduce tumorgenicity and reduce proliferation of certain cancer cell lines. It has also been shown to induce angiogenesis in endothelial cells and stimulate cell migration in many mesenchymal cell types. Recombinant human NOV is a 36.2 kDa protein containing 331 amino acid residues and it shares 80% and 81% amino acid identity with rat and murine NOV.

Product Specifications

Catalog ID 1150-01B9
MW ~36.2 kDa
Storage/Handling Store desiccated at -20°C.
View
Quick Add
1150-01B9-5 5 μg $ 76.00
1150-01B9-20 20 μg $ 112.00
1150-01B9-1000 1000 μg $ 1,795.00

NOV, Murine

Catalog ID Size Pricing
1350-01B9-5 5 μg $ 76.00
1350-01B9-20 20 μg $ 112.00
1350-01B9-1000 1000 μg $ 1,795.00

Description

NOV is a dynamically expressed, multifunctional matricellular protein of the CCN (CTGF/CYR61/NOV) family encoded by the NOV gene. It is expressed in certain tumors, including Wilm’s tumor and most nephroblastomas. Expression of NOV has been reported to reduce tumorgenicity and reduce proliferation of certain cancer cell lines. It has also been shown to induce angiogenesis in endothelial cells and stimulate cell migration in many mesenchymal cell types. Recombinant murine NOV is a 36.4 kDa protein containing 333 amino acid residues and it shares 92% and 82% amino acid identity with rat and human NOV.

Product Specifications

Catalog ID 1350-01B9
MW ~36.4 kDa
Storage/Handling Store desiccated at -20°C.
View
Quick Add
1350-01B9-5 5 μg $ 76.00
1350-01B9-20 20 μg $ 112.00
1350-01B9-1000 1000 μg $ 1,795.00

PRL, Murine

There is no image for PRL, Murine PRL, Murine
Catalog ID Size Pricing
3310-10-10 10 μg $ 76.00
3310-10-50 50 μg $ 112.00
3310-10-1000 1000 μg $ 781.00

Description

Murine Prolactin (PRL) is a peptide hormone that is secreted most notably from the pituitary gland where it acts in an endocrine fashion, but also from extra pituitary regions where it acts in an autocrine or paracrine fashion. PRL serves as a ligand for the prolactin receptor, PRLR. It is listed as having over 300 separate functions and is involved in more processes than any other pituitary hormone. PRL is most commonly known for its lactation stimulating effect, but also plays a role in reproductive behavior, homeostasis of electrolytes, growth and development, regulation of metabolism, immune system regulation, angiogenesis, and survival of cancer cells. Homozygous female knock-out mice lacking expression of PRL become infertile, whereas homozygous males were fully fertile.

Product Specifications

Catalog ID 3310-10
MW ~22.4 kDa
Storage/Handling Store desiccated at -20°C.
View
Quick Add
3310-10-10 10 μg $ 76.00
3310-10-50 50 μg $ 112.00
3310-10-1000 1000 μg $ 781.00

PRL, Rat

Catalog ID Size Pricing
3510-10-10 10 μg $ 76.00
3510-10-50 50 μg $ 112.00
3510-10-1000 1000 μg $ 781.00

Description

Rat Prolactin (PRL) is a peptide hormone that is secreted most notably from the pituitary gland where it acts in an endocrine fashion, but also from extra pituitary regions where it acts in an autocrine or paracrine fashion. It is listed as having over 300 separate functions and is involved in more processes than any other pituitary hormone. PRL is most commonly known for its lactation stimulating effect, but also plays a role in reproductive behavior, homeostasis of electrolytes, growth and development, regulation of metabolism, immune system regulation, angiogenesis, and survival of cancer cells. PRL acts as a ligand for the prolactin receptor, PRLR.

Product Specifications

Catalog ID 3510-10
MW ~22.6 kDa
Storage/Handling Store desiccated at -20°C.
View
Quick Add
3510-10-10 10 μg $ 76.00
3510-10-50 50 μg $ 112.00
3510-10-1000 1000 μg $ 781.00

PTH (1-34), Human

Catalog ID Size Pricing
3110-03-20 20 μg $ 76.00
3110-03-100 100 μg $ 112.00
3110-03-250 250 μg $ 250.00
3110-03-500 500 μg $ 424.00
3110-03-1000 1000 μg $ 701.00

Description

Human Parathyroid Hormone (PTH) is a hormone expressed and secreted as preproPTH by chief cells of the parathyroid glands when extracellular calcium levels are low. It is coexpressed with furin, the enzyme believed to be responsible for processing proPTH to PTH. PTH is a ligand for two different receptors, PTH1R in bone and kidney and PTH2R found in the CNS, pancreas, and placenta. PTH plays a major role in bone metabolism and calcium homeostasis, as well as renal excretion. Recombinant PTH (1-34) has been used to stimulate bone formation and bone resorption, increasing or decreasing bone mass depending on the mode of administration.

Product Specifications

Catalog ID 3110-03
MW ~4.1 kDa
Storage/Handling Store desiccated at -20°C.
View
Quick Add
3110-03-20 20 μg $ 76.00
3110-03-100 100 μg $ 112.00
3110-03-250 250 μg $ 250.00
3110-03-500 500 μg $ 424.00
3110-03-1000 1000 μg $ 701.00

PTH (1-84), Human

Catalog ID Size Pricing
3110-05-20 20 μg $ 76.00
3110-05-100 100 μg $ 112.00
3110-05-250 250 μg $ 250.00
3110-05-500 500 μg $ 424.00
3110-05-1000 1000 μg $ 701.00

Description

Human Parathyroid Hormone (PTH) is a hormone expressed and secreted as preproPTH by chief cells of the parathyroid glands when extracellular calcium levels are low. It is coexpressed with furin, the enzyme believed to be responsible for processing proPTH to PTH. PTH is a ligand for two different receptors, PTH1R in bone and kidney and PTH2R found in the CNS, pancreas, and placenta. PTH plays a major role in bone metabolism and calcium homeostasis, as well as renal excretion. In osteoblasts, PTH stimulates glycogenesis and the uptake of [1-(14)C]-2-deoxy-D-glucose (2DG).

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Product Specifications

Catalog ID 3110-05
MW ~9.4 kDa
Storage/Handling Store desiccated at -20°C.
View
Quick Add
3110-05-20 20 μg $ 76.00
3110-05-100 100 μg $ 112.00
3110-05-250 250 μg $ 250.00
3110-05-500 500 μg $ 424.00
3110-05-1000 1000 μg $ 701.00

PTH (7-34), Human

Catalog ID Size Pricing
3110-04-20 20 μg $ 76.00
3110-04-100 100 μg $ 112.00
3110-04-250 250 μg $ 250.00
3110-04-500 500 μg $ 424.00
3110-04-1000 1000 μg $ 701.00

Description

Human Parathyroid Hormone (PTH) is a hormone expressed and secreted as preproPTH by chief cells of the parathyroid glands when extracellular calcium levels are low. It is coexpressed with furin, the enzyme believed to be responsible for processing proPTH to PTH. PTH is secreted as a midregional peptide fragment (7-34) when extracellular calcium levels are high, offsetting the effects of PTH. PTH plays a major role in bone metabolism and calcium homeostasis, as well as renal excretion. PTH (7-34) is a PTH1R antagonist capable of stimulating proliferation and differentiation of hair follicles and epidermis while promoting cell survival by activation of Akt.


GoldBio growth factors are manufactured for RESEARCH USE ONLY and cannot be sold for human consumption!

Product Specifications

Catalog ID 3110-04
MW ~3.4 kDa
Storage/Handling Store desiccated at -20°C.
View
Quick Add
3110-04-20 20 μg $ 76.00
3110-04-100 100 μg $ 112.00
3110-04-250 250 μg $ 250.00
3110-04-500 500 μg $ 424.00
3110-04-1000 1000 μg $ 701.00

PTH (7-84), 15N, Human

Catalog ID Size Pricing
3110-12N-10 10 μg $ 76.00
3110-12N-50 50 μg $ 112.00
3110-12N-100 100 μg $ 212.00
3110-12N-250 250 μg $ 365.00
3110-12N-500 500 μg $ 701.00
3110-12N-1000 1000 μg $ 1,173.00

Description

Human Parathyroid Hormone (PTH) is a hormone expressed and secreted as preproPTH by chief cells of the parathyroid glands when extracellular calcium levels are low. PTH is coexpressed with furin, the enzyme believed to be responsible for processing proPTH to PTH. PTH is secreted as a C-terminal fragment (7-84) when extracellular calcium levels are high, offsetting the effects of PTH. PTH (7-84) acts as an antagonist for PTH1R, as well as a possible carboxy-terminus interacting PTH receptor. PTH and truncated PTH fragments play a major role in bone metabolism and calcium homeostasis, as well as renal excretion. This particular product has been labeled with the stable 15N isotope to help track its activity.

Product Specifications

Catalog ID 3110-12N
MW ~8.9 kDa
Storage/Handling Store desiccated at -20°C.
View
Quick Add
3110-12N-10 10 μg $ 76.00
3110-12N-50 50 μg $ 112.00
3110-12N-100 100 μg $ 212.00
3110-12N-250 250 μg $ 365.00
3110-12N-500 500 μg $ 701.00
3110-12N-1000 1000 μg $ 1,173.00

PTH (7-84), Human

Catalog ID Size Pricing
3110-12-20 20 μg $ 76.00
3110-12-100 100 μg $ 112.00
3110-12-250 250 μg $ 250.00
3110-12-500 500 μg $ 424.00
3110-12-1000 1000 μg $ 701.00

Description

Human Parathyroid Hormone (PTH) is a hormone expressed and secreted as preproPTH by chief cells of the parathyroid glands when extracellular calcium levels are low. PTH is coexpressed with furin, the enzyme believed to be responsible for processing proPTH to PTH. PTH is secreted as a C-terminal fragment (7-84) when extracellular calcium levels are high, offsetting the effects of PTH. PTH (7-84) acts as an antagonist for PTH1R, as well as a possible carboxy-terminus interacting PTH receptor. PTH and truncated PTH fragments play a major role in bone metabolism and calcium homeostasis, as well as renal excretion.

Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.

Product Specifications

Catalog ID 3110-12
MW ~8.8 kDa
Storage/Handling Store desiccated at -20°C.
View
Quick Add
3110-12-20 20 μg $ 76.00
3110-12-100 100 μg $ 112.00
3110-12-250 250 μg $ 250.00
3110-12-500 500 μg $ 424.00
3110-12-1000 1000 μg $ 701.00

Join our list to receive promos and articles.

Join Now