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Shop By Category | Antibiotics & Selection

Antibiotics & SelectionAntibiotics and Selection tools allow you to selectively control which cells can be found in your cultures.

GoldBio’s broad range of cell selection tools, including hundreds of antibiotics, antifungals and anticancers, plant selection and screening agents allow you to select, control and maintain your cell cultures with confidence and ease, no matter what cells you may be studying.
Displaying 1-20 of 345 results.
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1-Dodecylimidazole
Catalog ID
Size
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1-Dodecylimidazole product image
D-410-5
5 g
$ 211.00
D-410-10
10 g
$ 380.00
D-410-25
25 g
$ 807.00
D-410-50
50 g
$ 1452.00
D-410-100
100 g
$ 2614.00
Description
1-Dodecylimidazole is grouped with the imidazole organic compounds, containing an imidazole 1,3-C3N2 ring produced by natural products like alkaloids. Imidazole is amphoteric and aromatic. When an additional carbon and two hydrogens bind to the ring of this compound, 1-Dodecylimidazole can produce a 1-dodecyl-3-methylimidazolium cation. As an antifungal, 1-Dodecylimidazole can inhibit sterol C14 demethylation at low levels, 2,3-oxidosqualene cyclization and subsequent transmethylation when the quantity is raised. This has been postulated as a result of its binding to sterol carrier proteins. It functions as a hypocholesterolaemic agent by inhibiting cholesterol biosynthesis at the level of 2,3-oxidosqualene sterol cyclase. This substance has been an View product page →
Specifications
CAS Number 4303-67-7
Technical Resources

No resources are available for this product.

10-Deacetyl Baccatin III
Catalog ID
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10-Deacetyl Baccatin III product image
D-550-5
5 mg
$ 173.00
D-550-25
25 mg
$ 650.00
Description

10-Deacetyl baccatin III is an intermediate in the synthesis of the chemotherapeutic drug, paclitaxel (taxol). It is produced by and isolated from Taxus baccata. 10-Deacetyl baccatin III is an immiscible organic compound.

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Specifications
CAS Number 32981-86-5
Technical Resources
17-AAG
Catalog ID
Size
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17-AAG product image
A-950-500
500 μg
$ 39.00
A-950-1
1 mg
$ 56.00
A-950-5
5 mg
$ 141.00
Description

17-AAG (17-N-allylamino-17-demethoxygeldanamycin) is an antitumor agent derived from geldanamycin. It is studied for its role in the treatment of cancer. 17-AAG targets and inactivates Hsp90 (heat shock protein 90), which is expressed in a variety of cancer cells including lymphoma and leukemia. It has been shown to induce apoptosis in ALCL cells and cause c-Kit inhibition. 17-AAG has 100x more affinity for cancer cell Hsp90 than noncancer cell Hsp90.

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Specifications
CAS Number 75747-14-7
Technical Resources
2'-C-Methylcytidine
Catalog ID
Size
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2'-C-Methylcytidine product image
M-315-10
10 mg
$ 126.00
M-315-25
25 mg
$ 255.00
Description
2'-C-Methylcytidine is a nucleoside analog with antiviral properties. It has shown be a potent replication inhibitor, in vivo, towards multiple RNA viruses including hepatitus C virus (HCV). 2'-C-Methylcytidine has been shown inhibit viral RNA polymerase, disrupting replicon formation and preventing viral proliferation. While 2'-C-Methycytidine is a strong antiviral, it has exhibited low oral bioavailability. Product Specifications2'-C-MethylcytidineNM-107Formula: C10H15N3O5 MW: 257.24 g/molStorage/Handling: View product page →
Specifications
CAS Number 20724-73-6
Technical Resources

No resources are available for this product.

2,3,5-Triphenyltetrazolium chloride (TTC; Tetrazolium chloride)
Catalog ID
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2,3,5-Triphenyltetrazolium chloride (TTC; Tetrazolium chloride) product image
T-112-250
250 g
$ 778.00
T-112-1
1 kg
$ 1164.00
T-112-500
500 g
$ 1421.00
T-112-2.5
2.5 kg
$ 2771.00
Description

Tetrazolium red is used to visualize dehydrogenase enzyme activity. Initially, the tetrazolium solution is colorless but changes to red when it comes into contact with hydrogen. Tetrazolium red is used in a biochemical viability test for seeds. The test relies on dehydrogenase enzymes to release hydrogen ions, which subsequently reduce the colorless tetrazolium salt solution to a red compound called formazan. Living cells turn red while dead cells remain colorless.

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Specifications
CAS Number 298-96-4
Technical Resources
4-Methylumbelliferyl caprylate
Catalog ID
Size
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4-Methylumbelliferyl caprylate product image
M-540-1
1 g
$ 121.00
M-540-2.5
2.5 g
$ 273.00
M-540-5
5 g
$ 530.00
M-540-10
10 g
$ 990.00
Description
4-Methylumbelliferyl caprylate Octanoic acid 4-methylumbelliferyl ester 4-MU-caprylate MOLECULAR BIOLOGY GRADE C18H22O4 MW: 302.37 g/mol White to off-white crystalline powder Fluorogenic substrate for esterase with C8 activity, yielding a blue fluorescent solution upon cleavage. Used for the identification of Salmonella spp. based on the detection of caprylate esterase. Storage/Handling: Store at -15°C, and protect from light and humidity. Literature: 1. U. Bottiroli, F. Carozzi, Method for the immediate identification of Salmonella cultures. European Patent 326 6 35 B1 (1992). 2. P.M. Aguirre, et al., Rapid fluorescence method for screening Salmonella spp. from enteric differential agars. J. Clin. Microbiol. 1990, 28, 148. View product page →
Specifications
CAS Number 20671-66-3
Technical Resources
4-Nitrophenyl-α-D- galactopyranoside
Catalog ID
Size
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4-Nitrophenyl-α-D- galactopyranoside product image
N-280-2.5
2.5 g
$ 77.00
N-280-5
5 g
$ 135.00
N-280-10
10 g
$ 243.00
N-280-25
25 g
$ 585.00
Description
4-Nitrophenyl-α-D- galactopyranoside p-Nitrophenyl-alpha-D-galactoside PNP-alpha-D-Gal PNPG MOLECULAR BIOLOGY GRADE C12H15NO8 MW: 301.26 g/mol Off-white crystalline powder Chromogenic substrate yielding a soluble chromophor for the colorimetric assay of alpha-D-galactosidase upon cleavage. Used for the detection of hydrolases in tissues and membranes. Storage/Handling: Store at -15°C, and protect from light. Literature: 1. C.A. Dangelmaier, H. Holmsen, Determination of acid hydrolases in human platelets. Anal. Biochem. 1980, 104, 182. 2. G.J. Kaczorowski, et al., Specific labeling of the lac carrier protein in membrane vesicles of Escherichia coli by a photoaffinity reagent. Proc. Nat. Acad. Sci. USA 1980 , 77, 6319. View product page →
Specifications
CAS Number 7493-95-0
Technical Resources
4-Nitrophenyl-α-D- glucopyranoside (p-Nitrophenyl-α-D-glucoside; PNP-α-D-Glc)
Catalog ID
Size
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4-Nitrophenyl-α-D- glucopyranoside (p-Nitrophenyl-α-D-glucoside; PNP-α-D-Glc) product image
N-310-10
10 g
$ 180.00
N-310-25
25 g
$ 426.00
N-310-50
50 g
$ 810.00
N-310-100
100 g
$ 1538.00
Description
4-Nitrophenyl-α-D- glucopyranoside p-Nitrophenyl-alpha-D-glucoside PNP-alpha-D-Glc MOLECULAR BIOLOGY GRADE C12H15NO8MW: 301.26 g/mol Off-white crystalline powder Chromogenic substrate for alpha-D-glucosidase, yielding a yellow solution upon cleavage. Also used for the detection of glucansucrases and for yeast alpha-D-glucosidase and for crystal structure studies of the complexes of concanavalin A. Storage/Handling: Store at -15°C, and protect from light. Literature: 1. T.P. Binder, J.F. Robyt, p-Nitrophenyl alpha-D-glucopyranoside, a new substrate for glucansucrases. Carbohydr. R es. 1983, 124, 287. 2. D.E. Oliveira, et al., Permeabilization of yeast for in situ determination of alpha-glucosidase. Anal. Biochem. 1981, 113, 188. 3. B. Wimmer, et al., A novel type of thermostable alpha-D-glucosidase from Thermoanaerobacter thermohydrosulfuricus exhibiting maltodextrinohydrolase activity. Biochem. J. View product page →
Specifications
CAS Number 3767-28-0
Technical Resources
4-Nitrophenyl-α-D-glucopyranoside, beta-Anomer < 0.1%
Catalog ID
Size
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4-Nitrophenyl-&#945;-D-glucopyranoside, beta-Anomer < 0.1%  product image
N-311-50
50 g
$ 574.00
Description
p-Nitrophenyl α-D-glucopyranoside Empirical Formula: C12H15NO8 Molecular Weight: 301.25 Beilstein Registry Number: 92212EC Number: 223-189-3MDL number: MFCD00064088PubChem Substance ID: 24897484 View product page →
Specifications
CAS Number 3767-28-0
Technical Resources

No resources are available for this product.

4-Nitrophenyl-β-D- galactosidase (p-Nitrophenyl-β-D-galactoside; PNP-β-D-Gal)
Catalog ID
Size
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4-Nitrophenyl-&#946;-D- galactosidase (p-Nitrophenyl-&#946;-D-galactoside; PNP-&#946;-D-Gal) product image
N-290-10
10 g
$ 122.00
N-290-25
25 g
$ 285.00
N-290-50
50 g
$ 535.00
N-290-100
100 g
$ 1000.00
Description
4-Nitrophenyl-β-D- galactosidase p-Nitrophenyl-β-D-galactoside PNP-β-D-Gal MOLECULAR BIOLOGY GRADE C12H15NO8 MW: 301.26 g/mol White to off-white crystalline powder Chromogenic β-galactosidase substrate, yielding a yellow solution upon cleavage. Can be used for the detection of coliforms due to their β-galactosidase activity. Storage/Handling: Store at -15°C, and protect from light. View product page →
Specifications
CAS Number 3150-24-1
Technical Resources
5-Bromo-4-chloro-3-indoxyl butyrate
Catalog ID
Size
Pricing
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5-Bromo-4-chloro-3-indoxyl butyrate product image
B-300-1
1 g
$ 254.00
Description
X-butyrate MOLECULAR BIOLOGY GRADE C12H11BrClNO3 MW: 316.59 g/mol Can be used as a substrate for carboxyl esterase, yielding a blue precipitate upon cleavage. Storage/Handling: Store desiccated at -20°C. Protect from light. Store under inert gas. View product page →
Specifications
CAS Number 129541-43-1
Technical Resources
5-Bromo-4-chloro-3-indoxyl caprylate
Catalog ID
Size
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5-Bromo-4-chloro-3-indoxyl caprylate product image
B-320-2.5
2.5 g
$ 221.00
B-320-5
5 g
$ 353.00
B-320-10
10 g
$ 565.00
B-320-25
25 g
$ 1176.00
Description
5-Bromo-4-chloro-3-indoxyl octanoate; X-caprylate MOLECULAR BIOLOGY GRADE C16H19BrClNO2 MW: 372.70 g/mol A chromogenic substrate for esterase with C8 activity. 5-Bromo-4-chloro-3-indoxyl caprylate yields a blue precipitate when cleaved. Storage/Handling: Store at -20°C under inert gas. View product page →
Specifications
CAS Number 129541-42-0
Technical Resources
5-Bromo-6-chloro-3-indoxyl butyrate
Catalog ID
Size
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5-Bromo-6-chloro-3-indoxyl butyrate product image
B-310-500
500 mg
$ 245.00
B-310-1
1 g
$ 377.00
B-310-2.5
2.5 g
$ 726.00
B-310-5
5 g
$ 1117.00
Description
MagentaTM-butyrate MOLECULAR BIOLOGY GRADE C12H11BrClNO2 MW: 316.59 g/mol Used as a chromogenic substrate for carboxylesterase, yielding a magenta precipitate upon cleavage. Storage/Handling: Store at -20°C. Protect from light. View product page →
Specifications
CAS Number 873295-29-5
Technical Resources
5-Bromo-6-chloro-3-indoxyl caprylate
Catalog ID
Size
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5-Bromo-6-chloro-3-indoxyl caprylate product image
B-325-2.5
2.5 g
$ 191.00
B-325-5
5 g
$ 357.00
B-325-10
10 g
$ 667.00
B-325-25
25 g
$ 1557.00
Description
5-Bromo-6-chloro-3-indoxyl caprylate 5-Bromo-6-chloro-3-indoxyl octanoate Magenta™-caprylate MOLECULAR BIOLOGY GRADE C 16H19BrClNO2 MW: 372.70 g/mol Storage/Handling: Store desiccated at -20°C. Protect from light. View product page →
Specifications
CAS Number 209347-94-4
Technical Resources
5-Fluorocytosine
Catalog ID
Size
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5-Fluorocytosine product image
F-500-1
1 g
$ 131.00
F-500-5
5 g
$ 295.00
Description

5-Fluorocytosine is a fluorinated cytosine analog and antifungal agent. 5-fluorocytosine becomes 5-fluorouracil and is then incorporated into RNA, causing miscoding and inhibition of DNA synthesis. It is effective against Candida and Cryptococcus species and can be used as a negative selection agent in transgenic plants.

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Specifications
CAS Number 2022-85-7
Technical Resources
5-Fluorouracil
Catalog ID
Size
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5-Fluorouracil product image
F-440-1
1 g
$ 28.00
F-440-5
5 g
$ 70.00
Description
5-Fluorouracil (5-FU) is a uracil analog that has a fluorine atom on the fifth carbon position. It acts as a strong anti-cancer agent where its metabolization disrupts both RNA and DNA synthesis. 5-FU metabolites, Fluorodeoxyuridine triphosphate (FdUTP) and fluorouridine triphosphate (FUTP), imitate uracil and are incorporated into RNA strands which effectively inhibits further synthesis.Inhibition of DNA synthesis by 5-FU occurs through thymidylate synthase inhibition. A metabolite produced by 5-FU metabolism, fluorodeoxyuridine triphosphate (FdUTP), bind to the nucleotide binding site of thymidylate synthase. Halting this enzyme’s activity significantly diminishes deoxythymidine monophosphate (dTMP) production which consequently depletes dTMP within an organism.Product Specifications5-FluorouracilFluorouracilFormula: View product page →
Specifications
CAS Number 51-21-8
Technical Resources

No resources are available for this product.

6-Aminopenicillanic acid
Catalog ID
Size
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6-Aminopenicillanic acid product image
A-915-10
10 g
$ 40.00
A-915-25
25 g
$ 65.00
Description
6-Aminopenicillanic acid (6-APA) is the central component of penicillin β-lactam antibiotics which are generated by Penicillium. 6-APA forms from penicillin G after being catalyzed by penicillin acylases. This compound can be used to create semi-synthetic antibiotics that are effective against non-penicillinase forming bacterium, such as Streptococcus and some Staphylococcus.6-APA is used as precursor for antibiotic compounds ampicillin and amoxicillin. Antibiotic synthesis of 6-APA can be augmented with a supersaturated solution of nucleophiles. Other methods for enhancing effectiveness involves diminishing ionic strength in a reaction mixture along with the addition of 2-butanol. Implementing a pH gradient starting at pH 7 and View product page →
Specifications
CAS Number 551-16-6
Technical Resources

No resources are available for this product.

8-Hydroxyquinoline
Catalog ID
Size
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8-Hydroxyquinoline product image
H-605-25
25 g
$ 37.00
H-605-100
100 g
$ 68.00
H-605-500
500 g
$ 229.00
Description
8-Hydroxyquinoline is an organic compound that is used as a RNA inhibitor, anti-cancer agent and bidentate chelating agent. In vitro studies against Escherichia coli had shown 8-hydroxyquinoline inhibiting RNA polymerase activity. The enzyme’s activity was inhibited by chelating manganese, magnesium or zinc cofactors. Activity of 8-hydroxyquinoline toward RNA polymerase is broad and inhibits the synthesis of vertebrate RNA as well as proteins.8-Hydroxyquinoline has also been used as an immobile chelating agent to remove transition metals, alkali and alkaline cations from solutions or within organisms. Its capability to bind the positively charged metals has been shown in vivo to inhibit proteasome View product page →
Specifications
CAS Number 148-24-3
Technical Resources

No resources are available for this product.

Acalabrutinib
Catalog ID
Size
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Acalabrutinib product image
A-415-10
10 mg
$ 146.00
Description
Acalabrutinib (ACP-196) is an irreversible inhibitor of Bruton’s tyrosine kinase (BTK), which is responsible for the maturation of B-cells. Its high selectivity to bind the residue Cys481 in the active site of BTK is a sought after feature for oncology research. Studies on mice and human cells demonstrate the high affinity of ACP-196 and its low affinity toward similar proteins in T-cell maturation.Product SpecificationsAcalabrutinibACP-196Formula: C26H23N7O2 MW: 465.51 g/molStorage/Handling: View product page →
Specifications
CAS Number 1420477-60-6
Technical Resources

No resources are available for this product.

Aclarubicin HCl
Catalog ID
Size
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Aclarubicin HCl product image
A-101-5
5 mg
$ 72.00
Description

Aclarubicin HCl is an anticancer agent isolated from Streptomyces galilaeus. It functions by inhibiting nucleic acid synthesis and causing DNA and RNA to intercalate. It is also a topoisomerase II inhibitor. Aclarubicin has been shown to suppress progression of lymphoma or lung cancer. It has also been shown to counteract vasoconstriction in rats. Aclarubicin shows decreased cardiotoxicity when compared to similar anticancer agents.

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Specifications
CAS Number 75443-99-1
Technical Resources
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