Aminoglycosides

Aminoglycosides are antibacterial agents that target the 30S ribosomal subunit, resulting in an inability to read mRNA, ultimately producing a faulty or nonexistent protein. Aminoglycosides may act either as bactericidal or as bacteriostatic. Aminoglycosides are primarily used against aerobic, gram-negative bacteria such as Pseudomonas, or Enterobacter, but also have demonstrated limited function against some gram-positive bacteria. Many aminoglycosides, such as kanamycin, spectinomycin, streptomycin, and hygromycin B, are commonly used as selective agents in laboratory, bacterial screening protocols.
Showing 1-20 of 28 items.

Amikacin Hydrate

Catalog ID Size Pricing
A-530-1 1 g $ 81.00
A-530-5 5 g $ 293.00

Description

Amikacin hydrate is a broad-spectrum aminoglycoside antibiotic derived from kanamycin A. It is effective against gram-negative bacteria such as Pseudomonas aeruginosa and a variety of enteric species. It is also effective against Mycobacterium tuberculosis. Amikacin hydrate is freely soluble in aqueous solution.

Product Specifications

Catalog ID A-530
CAS # 1257517-67-1 / 37517-28-5 (anhydrous)
MW 585.60 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store desiccated at 4°C.
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A-530-1 1 g $ 81.00
A-530-5 5 g $ 293.00

Amikacin Sulfate, USP Grade

Catalog ID Size Pricing
A-532-5 5 g $ 48.00   $ 39.00
A-532-25 25 g $ 127.00   $ 102.00

Description

Amikacin sulfate (disulfate) is a broad-spectrum aminoglycoside antibiotic derived from kanamycin A. It is effective against gram-negative bacteria such as Pseudomonas aeruginosa and a variety of enteric species. It is also effective against Mycobacterium tuberculosis. Amikacin sulfate is freely soluble in aqueous solution.

Product Specifications

Catalog ID A-532
CAS # 39831-55-5
MW 781.76 g/mol
Storage/Handling Store at 4°C.
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A-532-5 5 g $ 48.00
$ 39.00
A-532-25 25 g $ 127.00
$ 102.00

Apramycin Sulfate

Catalog ID Size Pricing
A-600-1 1 g $ 37.00
A-600-5 5 g $ 83.00
A-600-10 10 g $ 104.00

Description

Apramycin is an aminoglycoside antibiotic useful against gram-negative bacteria such as E. coli and Salmonella species. It is used to study antibiotic resistance and protein synthesis translocation inhibition. Apramycin sulfate is freely soluble.

Product Specifications

Catalog ID A-600
CAS # 65710-07-8
MW 637.66 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store at 4°C.
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A-600-1 1 g $ 37.00
A-600-5 5 g $ 83.00
A-600-10 10 g $ 104.00

Dihydrostreptomycin Sulfate

Catalog ID Size Pricing
D-450-25 25 g $ 96.00
D-450-100 100 g $ 241.00

Description

Dihydrostreptomycin is an aminoglycoside antibiotic targeting gram-positive bacteria and Mycobacterium species. It is a derivative of streptomycin and commonly used to study aminoglycoside uptake. Dihydrostreptomycin sulfate is freely soluble in aqueous solution.

Product Specifications

Catalog ID D-450
CAS # 5490-27-7
MW 730.71 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store at 4°C.
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D-450-25 25 g $ 96.00
D-450-100 100 g $ 241.00

G-418 Sulfate

Catalog ID Size Pricing
G-418-1 1 g $ 30.00   $ 24.00
G-418-5 5 g $ 137.00   $ 110.00
G-418-10 10 g $ 229.00   $ 184.00
G-418-25 25 g $ 338.00   $ 271.00

Description

G-418 sulfate, also known as geneticin, is an aminoglycoside antibiotic similar in structure to gentamicin B1. It is commonly used in plant and mammalian cell culture as a selectable marker. It can be used to select for cells transformed with an iNOS promoter construct or neomycin resistance gene.

G-418 functions by causing a chain of nonsense mutations during translation, ultimately resulting in inhibition of polypeptide synthesis and protein elongation. Resistance to G-418 is conferred through the nptll gene in plant cells and the neo gene in mammalian cells, which encode aminoglycoside 3'-phosphotransferase. For gene selection applications, a kill curve can be made to determine the minimum effective G418 concentration to kill non-resistant cells. G418 disulfate is freely soluble in water.

Product Specifications

Catalog ID G-418
CAS # 108321-42-2
MW 692.71 g/mol
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G-418-1 1 g $ 30.00
$ 24.00
G-418-5 5 g $ 137.00
$ 110.00
G-418-10 10 g $ 229.00
$ 184.00
G-418-25 25 g $ 338.00
$ 271.00

Gentamicin Sulfate 50 mg/mL Solution

Catalog ID Size Pricing
G-400-SL10 10 mL $ 46.00
G-400-SL25 25 mL $ 68.00
G-400-SL50 50 mL $ 92.00
G-400-SL100 100 mL $ 115.00

Description

Gentamicin is a broad-spectrum aminoglycoside antibiotic effective against gram-negative and gram-positive species. In addition, gentamicin exhibits antimicrobial properties against species resistant to tetracycline, colistin, kanamycin, and chloramphenicol.

GoldBio’s antibiotic solutions are provided ready to use.

Product Specifications

Catalog ID G-400-SL
CAS # 1405-41-0
MW 575.67 g/mol
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G-400-SL10 10 mL $ 46.00
G-400-SL25 25 mL $ 68.00
G-400-SL50 50 mL $ 92.00
G-400-SL100 100 mL $ 115.00

Gentamicin Sulfate EZ Pak™ for 50 mg/mL Solution

Catalog ID Size Pricing
G-400-EZ10 10 mL $ 46.00
G-400-EZ25 25 mL $ 68.00
G-400-EZ50 50 mL $ 92.00
G-400-EZ100 100 mL $ 115.00

Description

The Gentamicin EZ Pak™ is the fastest and easiest way to make a set amount of sterile gentamicin solution. The kit includes pre-weighed gentamicin powder, a sterile filter and a sterile container for the filtered solution. No need to calculate, simply add the stated amount of deionized H2O, filter, and pour into the labeled bottle for easy usage. The EZ Pak™ includes high quality GoldBio gentamicin and the sterile solution is ready for tissue culture, bacterial media, or any number of uses.

Product Specifications

Catalog ID G-400-EZ
CAS # 1405-41-0
MW 575.67 g/mol
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G-400-EZ10 10 mL $ 46.00
G-400-EZ25 25 mL $ 68.00
G-400-EZ50 50 mL $ 92.00
G-400-EZ100 100 mL $ 115.00

Gentamicin Sulfate, USP Grade

Catalog ID Size Pricing
G-400-1 1 g $ 23.00   $ 19.00
G-400-5 5 g $ 34.00   $ 28.00
G-400-10 10 g $ 58.00   $ 47.00
G-400-25 25 g $ 88.00   $ 71.00
G-400-100 100 g $ 282.00   $ 226.00

Description

Gentamicin is an aminoglycoside, broad-spectrum antibiotic that effectively inhibits Gram-negative and Gram-positive cell growth. Gentamicin's mode of action is to bind to the 30S ribosomal subunit and interfere with protein synthesis.

It is commonly used in clinical in vitro microbiological antimicrobial susceptibility tests (panels, discs, and MIC strips) against gram-positive and gram-negative microbial isolates. Medical microbiologists use AST results to recommend antibiotic treatment options for infected patients.

Product Specifications

Catalog ID G-400
CAS # 1405-41-0
MW 575.67 g/mol
Storage/Handling Store desiccated at -20°C.
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G-400-1 1 g $ 23.00
$ 19.00
G-400-5 5 g $ 34.00
$ 28.00
G-400-10 10 g $ 58.00
$ 47.00
G-400-25 25 g $ 88.00
$ 71.00
G-400-100 100 g $ 282.00
$ 226.00

Hygro99

Catalog ID Size Pricing
H-271-500 500 mg $ 100.00
H-271-1 1 g $ 139.00

Description

Hygro99 is the purest form of Hygromycin B available. It is over 99% pure and should be used for the most sensitive applications and on the most sensitive cell lines. All impurities that might cause inhibition of resistant cell lines have been removed. In general, our Molecular Grade Hygromycin B (which is still ≥92 % pure and less expensive) will not adversely affect your cells and is suitable for most experiments.

Product Specifications

Catalog ID H-271
CAS # 31282-04-9
MW 563.52 g/mol
Storage/Handling Store desiccated at -20°C.
UN Number 3462
Item Class 6.1
Group Number I
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H-271-500 500 mg $ 100.00
H-271-1 1 g $ 139.00

Hygromycin B

Catalog ID Size Pricing
H-270-1 1 g $ 68.00   $ 55.00
H-270-2-1 2 x 1 g $ 127.00   $ 102.00
H-270-2.5 2.5 g $ 161.00   $ 129.00
H-270-5 5 g $ 281.00   $ 225.00
H-270-5-1 5 x 1 g $ 305.00   $ 244.00
H-270-10 10 g $ 506.00   $ 405.00
H-270-10-1 10 x 1 g $ 518.00   $ 415.00

Description

Hygromycin B is an aminoglycoside antibiotic isolated from Streptomyces hygroscopicus. It is commonly used to study protein synthesis. Aside from its efficacy against bacteria, fungi, and higher eukaryotic cells, hygromycin B is also an antiviral agent inhibiting translation upon selectively entering cells made permeable due to viral infection. It works as a standard selection antibiotic in gene experiments, especially for selection of hygromycin resistance gene transformed cells.

Product Specifications

Catalog ID H-270
CAS # 31282-04-9
MW 527.52 g/mol
Storage/Handling Store desiccated at -20°C.
UN Number 3462
Item Class 6.1
Group Number I
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H-270-1 1 g $ 68.00
$ 55.00
H-270-2-1 2 x 1 g $ 127.00
$ 102.00
H-270-2.5 2.5 g $ 161.00
$ 129.00
H-270-5 5 g $ 281.00
$ 225.00
H-270-5-1 5 x 1 g $ 305.00
$ 244.00
H-270-10 10 g $ 506.00
$ 405.00
H-270-10-1 10 x 1 g $ 518.00
$ 415.00

Hygromycin B EZ Pak™ for 50 mg/mL Solution

Catalog ID Size Pricing
H-270-EZ25 25 mL $ 127.00
H-270-EZ50 50 mL $ 206.00
H-270-EZ100 100 mL $ 315.00

Description

The Hygromycin B EZ Pak™ is the fastest and easiest way to make a set amount of sterile hygromycin B solution. The kit includes pre-weighed hygromycin B powder, a sterile filter and a sterile container for the filtered solution. No need to calculate, simply add the stated amount of deionized H2O, filter, and pour into the labeled bottle for easy usage. The EZ Pak™ includes high quality GoldBio hygromycin B and the sterile solution is ready for tissue culture, bacterial media or any other appropriate use.

Product Specifications

Catalog ID H-270-EZ
CAS # 31282-04-9
MW 527.52 g/mol
UN Number 3462
Item Class 6.1
Group Number I
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H-270-EZ25 25 mL $ 127.00
H-270-EZ50 50 mL $ 206.00
H-270-EZ100 100 mL $ 315.00

Kanamycin Monosulfate 50 mg/mL Solution

Catalog ID Size Pricing
K-120-SL25 25 mL $ 46.00
K-120-SL50 50 mL $ 68.00
K-120-SL100 100 mL $ 92.00

Description

Kanamycin is an aminoglycoside antibiotic isolated from Streptomyces kanamyceticus. It is effective against gram-positive and gram-negative bacteria as well as Mycoplasma species. Kanamycin is commonly used to select for bacteria that have been transformed with a kanamycin-resistant gene and plant tissues that have the NPT II (APH3) gene incorporated in them. Kanamycin is very soluble in aqueous solution and is typically used in concentrations of 50-100 µg/ml.

Product Specifications

Catalog ID K-120-SL
CAS # 25389-94-0
MW 582.58 g/mol
Grade MOLECULAR BIOLOGY GRADE
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K-120-SL25 25 mL $ 46.00
K-120-SL50 50 mL $ 68.00
K-120-SL100 100 mL $ 92.00

Kanamycin Monosulfate EZ Pak™ for 50 mg/mL Solution

Catalog ID Size Pricing
K-120-EZ25 25 mL $ 46.00
K-120-EZ50 50 mL $ 68.00
K-120-EZ100 100 mL $ 92.00

Description

The Kanamycin Monosulfate EZ Pak™ is the fastest and easiest way to make a set amount of sterile kanamycin monosulfate solution. The kit includes pre-weighed kanamycin monosulfate powder, a sterile filter and a sterile container for the filtered solution. No need to calculate, simply add the stated amount of deionized H2O, filter, and pour into the labeled bottle for easy usage. The EZ Pak™ includes high quality GoldBio kanamycin monosulfate and the sterile solution is ready for tissue culture, bacterial media, or any number of uses.

Product Specifications

Catalog ID K-120-EZ
CAS # 25389-94-0
MW 582.58 g/mol
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K-120-EZ25 25 mL $ 46.00
K-120-EZ50 50 mL $ 68.00
K-120-EZ100 100 mL $ 92.00

Kanamycin Monosulfate, USP Grade

Catalog ID Size Pricing
K-120-5 5 g $ 23.00   $ 19.00
K-120-10 10 g $ 44.00   $ 36.00
K-120-25 25 g $ 92.00   $ 74.00
K-120-50 50 g $ 173.00   $ 139.00
K-120-100 100 g $ 323.00   $ 259.00
K-120-250 250 g $ 748.00   $ 599.00

Description

Kanamycin is an aminoglycoside antibiotic isolated from Streptomyces kanamyceticus. It is effective against gram-positive and gram-negative bacteria as well as Mycoplasma species. Kanamycin is commonly used to select for bacteria that have been transformed with a kanamycin-resistant gene and plant tissues that have the NPT II (APH3) gene incorporated in them. Kanamycin is very soluble in aqueous solution and is typically used in concentrations of 50-100 µg/ml.

Product Specifications

Catalog ID K-120
CAS # 25389-94-0
MW 582.58 g/mol
Storage/Handling Store desiccated at -20°C.
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K-120-5 5 g $ 23.00
$ 19.00
K-120-10 10 g $ 44.00
$ 36.00
K-120-25 25 g $ 92.00
$ 74.00
K-120-50 50 g $ 173.00
$ 139.00
K-120-100 100 g $ 323.00
$ 259.00
K-120-250 250 g $ 748.00
$ 599.00

Micronomicin Sulfate

Catalog ID Size Pricing
M-870-10 10 g $ 79.00

Description

Micronomicin sulfate is an aminoglycoside antibiotic effective against gram-negative bacteria. It is freely soluble in water.

Product Specifications

Catalog ID M-870
CAS # 66803-19-8
MW 561.65 g/mol
Grade MOLECULAR BIOLOGY GRADE
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M-870-10 10 g $ 79.00

Neomycin Sulfate, USP Grade

Catalog ID Size Pricing
N-620-5 5 g $ 22.00
N-620-10 10 g $ 31.00
N-620-25 25 g $ 48.00
N-620-100 100 g $ 84.00
N-620-500 500 g $ 395.00

Description

Neomycin is a broad-spectrum aminoglycoside antibiotic isolated from Streptomyces species. It targets gram-negative and gram-positive bacteria. Neomycin can also be used as a selection agent for prokaryotic cells transformed with the neo gene or NPT II resistance gene and to study toxic antibacterial side effects. In addition, neomycin is a calcium channel protein inhibitor and DNase I inhibitor. It can be used in a variety of cell culture applications

Product Specifications

Catalog ID N-620
CAS # 1405-10-3
MW 908.88 g/mol
Storage/Handling Store at 4°C.
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N-620-5 5 g $ 22.00
N-620-10 10 g $ 31.00
N-620-25 25 g $ 48.00
N-620-100 100 g $ 84.00
N-620-500 500 g $ 395.00

Netilmicin Sulfate

Catalog ID Size Pricing
N-630-5 5 mg $ 541.00

Description

Netilmicin sulfate is an aminoglycoside antibiotic similar to gentamicin and a derivative of sisomicin. It targets gram-negative bacteria as well as some gram-positive bacteria. Additionally, netilmicin has been used to study aminoglycoside resistance and susceptibility of Pseudomonas aeruginosa and Pseudomonas pseudomallei. It can be detected using liquid chromatography.

Product Specifications

Catalog ID N-630
CAS # 56391-57-2
MW 720.75 g/mol
Grade MOLECULAR BIOLOGY GRADE
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N-630-5 5 mg $ 541.00

Paromomycin Sulfate, USP Grade

Catalog ID Size Pricing
P-700-5 5 g $ 53.00
P-700-25 25 g $ 106.00
P-700-100 100 g $ 212.00

Description

Paromomycin is an aminoglycoside antibiotic isolated from Streptomyces rimosus. It targets a variety of gram-negative and gram-positive bacteria as well as several protozoan species. It displays activity similar to that of neomycin. Paromomycin sulfate is freely soluble.

Product Specifications

Catalog ID P-700
CAS # 1263-89-4
MW 713.71 g/mol
Storage/Handling Store at 4°C.
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P-700-5 5 g $ 53.00
P-700-25 25 g $ 106.00
P-700-100 100 g $ 212.00

Ribostamycin Sulfate

Catalog ID Size Pricing
R-400-250 250 mg $ 244.00
R-400-1 1 g $ 536.00

Description

Ribostamycin is an aminoglycoside antibiotic isolated from Streptomyces ribosifidicus. It is a broad-spectrum antibiotic targeting gram-positive and gram-negative bacteria. Ribostamycin has been used to in pharmacokinetic studies and to study kidney toxicity. It is also an inhibitor of protein disulfide isomerase (PDI).

Product Specifications

Catalog ID R-400
CAS # 53797-35-6
MW 552.55 g/mol
Grade MOLECULAR BIOLOGY GRADE
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R-400-250 250 mg $ 244.00
R-400-1 1 g $ 536.00

Sisomicin Sulfate

Catalog ID Size Pricing
S-350-500 500 mg $ 122.00
S-350-1 1 g $ 213.00

Description

Sisomicin is a broad-spectrum aminoglycoside antibiotic isolated from Micromonospora inyoensis. It is related to gentamicin and targets gram-negative and gram-positive bacteria such as Klebsiella species, E. coli, P. aeruginosa, Enterobacter species, and Proteus species. It has been used in disk and tube dilution sensitivity assays.

Product Specifications

Catalog ID S-350
CAS # 53179-09-2
MW 692.72 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store at 4°C.
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S-350-500 500 mg $ 122.00
S-350-1 1 g $ 213.00

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